Title: The systems biology of a single cell
ٰ: Single-cell genomics technologies have facilitated the compilation of cell atlases across organisms, thereby resolving tissues into cell types and highlighting marker genes that can be targeted. In addition to these exciting applications, “multimodal” measurements from single-cell enable the study of dynamic processes in cells. We will discuss the statistical and mathematical modeling that enables such studies, with a view towards elucidating the systems biology of cells.
Short bio:
Lior Pachter was born in Ramat Gan, Israel, and grew up in Pretoria, South Africa where he attended . After receiving a B.S. in Mathematics from in 1994, He left for where he was awarded a in 1999. He then moved to the where he was a postdoctoral researcher (1999-2001), assistant professor (2001-2005), associate professor (2005-2009), and until 2018 the Raymond and Beverly Sackler professor of computational biology and professor of mathematics and molecular and cellular biology with a joint appointment in computer science. Since January 2017 he has been the Bren professor of computational biology at Caltech.
His research interests span the mathematical and biological sciences, and he has authored over 100 research articles in the areas of algorithms, combinatorics, comparative genomics, algebraic statistics, molecular biology and evolution. He has taught a in mathematics, computational biology and genomics. He is a and has been awarded a , a , the , and a Federal Laboratory Consortium award for the successful technology transfer of widely used sequence alignment software developed in his group (Bio is from Prof Pachter’s personal website).
The talk will be followed by the reception.
More details soon.