BibTex format
°ª²¹°ù³Ù¾±³¦±ô±ðµ÷´³´Ç²õ²¹-°ä³Ü±ô±ô±ð°ùé:2026:10.1183/23120541.00813-2026,
author = {Josa-Culleré, A and Koch, S and Demeyer, H and Troosters, T and Hopkinson, NS and Vogiatzis, I and Frei, A and Gimeno-Santos, E and Alcaraz-Serrano, V and Buekers, J and Delgado-Ortiz, L and Ã�lvarez, P and Cirach, M and ValentÃn, A and Garcia-Olivé, I and Rodriguez-Chiaradia, DA and Maetzler, W and Hansen, C and Jansen, C-P and Rochester, L and Del, Din S and Cereatti, A and Caulfield, B and Singleton, D and Yarnall, A and Gassner, H and Garcia-Aymerich, J},
doi = {10.1183/23120541.00813-2026},
journal = {ERJ Open Research},
pages = {00813--2026},
title = {Interaction of walking activity and long-term air pollution on exacerbation rate in COPD},
url = {http://dx.doi.org/10.1183/23120541.00813-2026},
year = {2026}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - <jats:sec> <jats:title>Background</jats:title> <jats:p>Regular walking activity can improve the prognosis in people with chronic obstructive pulmonary disease (COPD). However, its benefit may be reduced when living in highly polluted areas.</jats:p> </jats:sec> <jats:sec> <jats:title>Aim</jats:title> <jats:p>To assess the combined effects of walking activity and air pollution on the rate of moderate-to-severe exacerbation in COPD.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p> This prospective cohort study included 262 people with COPD from five European countries (United Kingdom, Spain, Belgium, Switzerland, Greece). Regular walking activity amount (walking bout step count, walking duration) and intensity (90thpercentile (P90) and average walking speed) was measured at baseline for seven days <jats:italic>via</jats:italic> single wearable devices. Residential concentrations of particulate matter<2.5µm (PM <jats:sub>2.5</jats:sub> ), black carbon (BC), nitrogen dioxide (NO <jats:sub>2</jats:sub> ) and ozone (O <jats:sub>3</jats:sub> ) were estimated using land-use regression models for the previous two years. Moderate-to-severe exacerbations over a two-year follow-up were obtained from medical records and paper diaries. We estimated the interaction between walking activity and air pollution on long-term exacerbation rate with multivariable mixed-effects negative binomial models. </jats:p>
AU - Josa-Culleré,A
AU - Koch,S
AU - Demeyer,H
AU - Troosters,T
AU - Hopkinson,NS
AU - Vogiatzis,I
AU - Frei,A
AU - Gimeno-Santos,E
AU - Alcaraz-Serrano,V
AU - Buekers,J
AU - Delgado-Ortiz,L
AU - �lvarez,P
AU - Cirach,M
AU - ValentÃn,A
AU - Garcia-Olivé,I
AU - Rodriguez-Chiaradia,DA
AU - Maetzler,W
AU - Hansen,C
AU - Jansen,C-P
AU - Rochester,L
AU - Del,Din S
AU - Cereatti,A
AU - Caulfield,B
AU - Singleton,D
AU - Yarnall,A
AU - Gassner,H
AU - Garcia-Aymerich,J
DO - 10.1183/23120541.00813-2026
EP - 2026
PY - 2026///
SP - 00813
TI - Interaction of walking activity and long-term air pollution on exacerbation rate in COPD
T2 - ERJ Open Research
UR - http://dx.doi.org/10.1183/23120541.00813-2026
UR - https://doi.org/10.1183/23120541.00813-2026
ER -