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In addition to the routine diagnostic services offered by MDU we also undertake specialist laboratory assays in support of clinical research projects, generally on batches of samples rather than in real-time. Currently available methods include:

• Ultra-sensitive detection and quantification of plasma-virus HIV-1 using real-time PCR to a level of <5 RNA copies/ml.
• Ultra-sensitive HIV-1 DNA PCR down to a single molecule.
• Bespoke PCR amplification, consensus and deep sequencing and SNiP analysis of any RNA or DNA target by conventional (Sanger) or next-generation (NGS – MiSeq) sequencing.
• Ribosomal 16S detection and identification via DNA sequencing.
• Support for clinical trials, particularly viable PBMC processing and storage.

Should you wish to utilise any of these services, or discuss other requirements for molecular diagnostic methods for infectious-disease-related projects, please contact the Unit Head or Unit Manager. We are always pleased to have new challenges.

Unit Head - Professor Graham Taylor (g.p.taylor@imperial.ac.uk)
Deputy Head of Unit - Anjna Badhan (anjna.badhan@imperial.ac.uk)

We are prepared to consider any request for specialist molecular diagnostic tests.